User requirement specification for Gas Chromatography (GC)
User requirement specification for Gas Chromatography (GC)
- General requirement
URS No. | AS per URS numbering system |
Name of Equipment/Instrument /System | GAS CHROMATOGRAPHY SYSTEM |
Area / Department | GC room / Quality control |
Description of Equipment/Instrument/System | Gas Chromatography system with Head space |
- Technical specification:
General and Technical specification shall be mention as per Equipment/Instrument/System
Sr. No. | Particulars | Requirements / Specifications | Remark |
1 | Oven | · Provides easy access to columns and gives excellent temperature control and fast cool-down times for maximum productivity.
· All temperature and time functions are microprocessor controlled and are shown on the touch-screen display. · Software selectable coolant time-out and coolant cut-in temperatures. |
NA |
2 | Pneumatics | · A full range of pneumatic options provides optimum performance with all types of columns and detectors.
· There are up to 12 PPC zones configured as 2 carrier (2 zones each), 2 detector (2 zones each) and 4 auxiliary channels · PPC or manual pneumatics are available for all injectors · PPC provides direct setting of split flow rates and ratios · Pneumatic program rates: 0-100.0 psi/min 0-100.0 mL/min 0-200.0 cm/sec or ballistic |
NA
|
4 | Detector pneumatics | · PPC or manual pneumatics are available for all detectors
· PPC provides direct setting in mL/min |
NA |
5 | Auxiliary pneumatics | · Four auxiliary zones
· PPC provides direct setting in mL/min, psig or kPa · Auxiliary PPC zones compensate for variations in ambient temperature for maximum stability |
NA |
6 | Autosampler | · Built-in syringe auto sampler for maximum sampling capabilities.
· All control is accomplished through the keyboard or by a data system. |
NA |
7 | Injectors | · Should support a comprehensive array of injectors that provides accuracy and precision to all of your sampling applications.
· Up to two injectors may be installed and operated with independent temperature control. |
NA |
8 | Packed-column injector | · Removable glass liner for trapping non-volatile residues
· Adapter for on-column injection to wide-bore capillary columns · 50 °C to 450 °C in 1 °C increments · 1/8-inch fitting · 1/4-inch column adapter available · Manual pneumatics – choice of flow controller with headpressure gauge, or flow controller with head-pressure gauge and digital display of flow · PPC pneumatics – programmed flow or pressure includes readout which displays pressure or column flow. |
NA |
9 | Split/split less capillary injector | · Split ratio easily adjustable for a wide range of analysis conditions.
· Charcoal trap in split vent prevents contamination of split valve and lab air · Two choices of liner: 2-mm and 4-mm internal diameter · 50 °C to 450 °C in 1 °C increments · Manual pneumatics – pressure regulator (0-60 psig) for digital display of column head pressure. Automatic control of split vent solenoid valve · PPC pneumatics – four software configurable modes: programmed flow, programmed pressure, programmed velocity or constant flow. Vacuum compensation software selectable · PPC pneumatics include automatic control of split vent by split flow or split ratio |
NA |
10 | Programmable on-column capillary injector | · Temperature-programmable inlet
· 50 °C to 500 °C in 1 °C increments · Heating rate of 1 °C/min to 200 °C/min or ballistic · Cools down from 380 ˚C to 50 ˚C in less than 6 minutes, while the oven is cooling in the same temperature range and with an FID at 380 ˚C · 1/16-inch fitting · Manual pneumatics – choice of flow controller with head-pressure gauge, or flow controller with head-pressure gauge and digital display of flow · PPC pneumatics include readout which displays pressure and column flow |
NA |
11 | PSS – programmable split/splitless capillary injector | · Temperature-programmable inlet
· Large-volume injection of up to 50 µL with autosampler, 150 µL manually · Three-ramps temperature program · Split ratio easily adjustable for a wide range of analysis conditions · Three choices of liner available: 1-mm and 2-mm i.d. and on-column · Charcoal trap in split vent prevents contamination of split valve and lab air · 50 °C to 500 °C in 1 °C increments · Cools down from 380 ˚C to 50 ˚C in less than 5 minutes, while the oven is cooling in the same temperature range and with an FID at 380 ˚C · Heating rate of 1 °C/min to 200 °C/min or ballistic · 1/16-inch fitting · Manual pneumatics – pressure regulator (0-60 psig) for digital display of column head pressure. Automatic control of split vent solenoid valve · PPC pneumatics – four software configurable modes: programmed flow, programmed pressure, programmed velocity or constant flow. · PPC pneumatics include automatic control of split vent by split flow or split ratio |
NA |
12 | Software | · Complete independence of the column from injectors or detectors
· Can assist users in removing unwanted sample residue from columns after analysis or switching between injectors and detectors for analytical flexibility · Easy setup configuration change, without requiring service information · Available only with PPC pneumatics |
NA |
13 | PreVent | · Available PSS and PPC pneumatics
· Includes injector and detector restrictors · To prevents higher boiling components or residues from going through the column and the detector · Enhanced large-volume injection (ELVI) mode isolates the column and detector from the effects of high levels of solvent. · Isolation mode allows a septum change without interrupting carrier flow. · Mode to eliminate contamination by preventing heavy components in the sample from reaching the expensive and retentive chromatographic column. Allows back flushing during chromatographic run. · Mode to allow changing of columns without cooling and venting. |
NA |
14 | Gas sampling valves | · Wide offering of 4-, 6-, 8- and 10-port valves • Large range of valved systems and standard analyzers available
· Keyboard controlled · 1/16- or 1/8-inch fittings |
NA |
15 | Detectors | · A wide choice of detectors optimized for sensitivity and selectivity for Flame Ionization Detector, the Thermal Conductivity Detector, the Electron Capture Detector, and/or environmental-specific detectors,
· Every detector is available with PPC or manual pneumatics. |
NA |
16 | Flame Ionization Detector (FID) | · Air flow designed to minimize contamination and residue buildup
· 1/8-inch fittings; also includes 1/16-inch capillary adaptor · Manual pneumatics – pressure regulator for hydrogen, needle valve for air · PPC pneumatics – software flow control of hydrogen and air · “Flame out” warning and ready interlock · Automatic ignite on units installed with PPC |
NA |
17 | Touch-screen graphical user interface | · language support-English
· Real-time graphic display of chromatogram · Injection countdown for manual injections · Column pressure/flow/velocity calculator · More upgradable firmware · Preventative maintenance counter · Password protection · Graphical display of temperature and pneumatic programs · Status-summary screen · Log file • Resolution: 240 x 320 · 256-color display · Meaningful error/alarm messages |
NA |
18 | TurboMatrix HS 40 | · Mid-capacity automated headspace sampler includes a built-in trap to concentrate samples to increase system sensitivity.
· Standard 9mL or 22mL sample vials can be used and up to 40 vials can be loaded into the removable vial magazine for automated analysis. · Overlapping thermo statting of up to 12 vials in Constant Mode for maximum productivity. · Automatic system and vial leak checks performed before analysis provide assurance of precision and sensitivity. |
NA |
- Electrical Requirements;
Sr. No. | Particulars | Requirements / Specifications | Remark |
1 | Power | Works on 230 V AC single phase 50 Hz. | NA |
- Components/Parts/Accessories Requirements:
Sr. No. | Particulars | Requirements / Specifications | Remark |
1 | Number of Trays | 2 Numbers | NA |
- Safety Requirements:
Sr. No. | Particulars | Requirements / Specifications | Remark |
1 | General | Ø PLC display head tighter should be well. | NA |
- GMP Requirements:
Sr. No. | Particulars | Requirements / Specifications | Remark |
1 | GMP Compliance | Software should be in compliance with 21 CFR part 11. | NA |
2 | Software type | Database software | NA |
3 | Audit trail policy | Audit trail policy shall be defined for user log in, log out activity, application errors / Errors during operation and operation logs. | NA |
- Documents Requirements:
Sr. No. | Particulars | Requirements / Specifications | Remark | |
1 | Design qualification | Document shall be in accordance with URS | NA | |
2 | /IQ/OQ/PQ protocol and report | Document shall be available | NA | |
- Specific / Other requirements:
Sr. No. | Particulars | Requirements / Specifications | Remark |
1 | General | 1. Provision for connection to the printer/server
2. Operating of machine should user friendly 3. All parts should be easily assemble and easy to remove. 4. All parts should be easy to clean. 5. Supplier should provide support in case of any breakdown. 6. The supplier should install the equipment and provide the necessary training to the user for operation and cleaning. 7. The Supplier should provide all required documents. |